Percutaneous Needle Biopsy-An Assertive Tool In The Diagnosis of Bone Tumors in Under Developed Countries.

Our study on 106 cases of bone tumors aims at correlating the clinical, radiological and cytological findings of benign and malignant tumors of bone and evaluating the usefulness of percutaneous biopsy as a diagnostic tool in underdeveloped countries. Giant cell lesions were the most common benign tumor, 42 cases (84%) and giant cell tumor was the most common giant cell lesion in our study, 27 (64.3%). Round cell tumor appeared to be the most common malignant tumor of bone, 20 cases (35.7%). Osteosarcoma represented 15 cases (14.2%) of all bone tumors and 26.8% of all malignant bone tumors in our study. Final histopathological diagnosis was available only in 54 cases. Out of which 53 cases showed concordance with previous cytological diagnosis. Only a single case of chondrosarcoma was misdiagnosed as chondroma on FNAC (false negative). The sensitivity and specificity of FNAC was 96.0% and 100% respectively while positive predictive value and negative predictive values were 100% and 96.7% respectively. The diagnostic accuracy in our study was 98.1%.

Evaluation of Misoprostol in the Medical Management of Abortion.

The present study was carried out to compare the safety and efficacy of Misoprostol with Surgical Evacuation in the management of abortion. 100 women as specified by the inclusion and exclusion criteria were recruited for this prospective observational study. 50 subjects (Group A) were managed medically by Misoprostol and 50 subjects (Group B) underwent Surgical Evacuation. Clinical outcome, time taken for expulsion, number of doses required, mean duration of hospital stay, mean analgesic requirement, mean blood loss and side effects were compared between the two groups. It was concluded that vaginal administration of Misoprostol is a safe, effective and cheap alternative to surgical evacuation. No serious adverse effects were observed with Misoprostol.

Mammography-guided stereotactic fine needle aspiration cytology of breast lesions.

The purpose of the present study was to evaluate the efficacy of mammographic guided stereotactic fine needle aspiration cytology in 136 patients with breast lesions including mammographic features, cytomorphological findings and nuclear grading in malignant cases. Majority of the cases were predictable correctly by combination of the three modalities of diagnosis viz, clinical examination, mammography and cytology.